April 1, 2026

Science Chronicle

A Science and Technology Blog

April 1, 2026

Science Chronicle

A Science and Technology Blog

Cancer

Breast cancerCancerInfluenzaLung cancerSARS-CoV-2

Can viral infections lead on to cancer recurrence?

A study suggests that a viral infection such as influenza and SARS/CoV-2 can set off an inflammatory cascade that “wakes up” the sleeping cancer cells located in distant organs such as lungs and bone marrow, leading them to proliferate

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CancerChemotherapyDrug resistanceGlioblastoma

Disarming a Tough Brain Cancer: How to Tackle Drug Resistance in Glioblastoma

Rather than trying to develop even stronger chemotherapy drugs, our approach aims to make cancer cells more sensitive to existing treatments by blocking their defence mechanisms. In this case, blocking TLK1 protein’s activity weakens the ability of cancer cells to survive, making it easier to kill them

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CancerPersonalised medicineThyroid cancer

Two studies shed new genetic insights into thyroid cancer in Indian patients

The indentification of two critical markers — DUOX2 and THRA — will help in better predicting which patients might face aggressive thyroid cancer disease or recurrence. For papillary thyroid cancer, this might mean developing targeted therapies for the novel subtype (iBR) or using DUOX2 for early detection. For anaplastic thyroid cancer, targeting THRA-driven plasticity could lead to breakthroughs for a cancer with few options

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CancerChemotherapyDNA damageGenome sequencing

A genomic view of DNA damage in chemotherapy

Seventeen of 23 individuals exposed to chemotherapy had far more genetic mutations than could be explained by normal aging. Even more revealing was the discovery of eight unique mutational signatures that were found only in the chemotherapy group. While some of these fingerprints matched the known damage profiles of certain chemo drugs, four of them were entirely new to science, uncovering previously unknown ways these treatments can alter our DNA

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CancerChewing tobaccoTobacco

Chew on this: Smokeless tobacco increases oral cancer risk by over 19 times in elderly people

In people older than 60 years, smokeless tobacco increased the odds of developing oral cancer by 19.5 times compared to

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CancerCervical cancerHealthNon-communicable diseasesVaccines

Study in Scotland finds zero cervical cancer cases among women vaccinated early

This study showed a greater risk reduction than predicted for girls vaccinated at age 12 or 13 years A population-based

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CancerHealthNon-communicable diseasesResearch

IACS scientists discover a new target for cancer treatment

A combination of inhibitors that target different aspects of cell cycle and DNA replication makes it hard for cancer cells

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Animal trialsCancerHealthResearch

Indian team uses repurposed drug to treat oral cancer subtype

In animal studies, the FDA-approved deworming drug was able to significantly inhibit the tumour cells and improve the survival rate

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CancerClinical trialHealthNon-communicable diseases

Can resveratrol-copper be used to prevent metastasis without trials?

A new research challenges the dogma that toxicity caused by chemotherapy is due to the direct damaging effect of drugs

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CancerCervical cancerVaccines

Serum’s HPV vaccine non-inferior to Gardasil

A phase-2/3 trial of Serum Institute of India’s human papillomavirus (HPV) vaccine Cervavac conducted at 12 tertiary care hospitals across

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CancerDrugsNon-communicable diseases

With pooled procurement, cancer drugs cost 82% less in India

In 1995, Tamil Nadu pioneered the centralised procurement and distribution of drugs and medicines to government hospitals across the State.

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CancerNon-communicable diseasesResearch

The role of the Y chromosome in cancer outcomes studied

Two studies have shed light on the role of the Y chromosome in cancer outcomes, in which males are often more adversely affected than females

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Breast cancerCancerResearch

Breast cancer: more insights into how hormonal therapy works

Work carried out by researchers from the Integrated Cancer Genomics Laboratory at the Advanced Centre for Training, Research, and Education in Cancer

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