Drug development

December 9, 2025 Abhor Gupta Karthik Raman

PURE: An AI Tool Makes Designing Safer, More Effective Medicines Easier

An AI tool developed by IIT Madras has made discovery of highly safe, effective drug analogues easily possible. In the case of the FDA-approved cancer drug Sorafenib, starting from its original structure, PURE produced hundreds of thousands of possible analogues, and then narrowed them down using basic drug-likeness filters. A manageable group of candidates that were selected exhibited docking scores comparable to, and in some cases, superior to those of Sorafenib

Clinical trial Drug development Ethics Research

May 7, 2025 Prasad Ravindranath

FDA uncovers ‘significant’ data falsification by Indian company, rejects all studies

FDA has said that the Mumbai-based Raptim Research has been “responsible for the creation of false in vitro study data”

Antibiotic resistance Drug development Drug resistance Health Research Science

August 25, 2018 Prasad Ravindranath

IIT Roorkee finds new drug target for antibiotic resistant bacteria Acinetobacter baumannii

IIT Roorkee researchers have identified the RNA protein Hfq as a potential drug target. Once the Hfq gene is removed,

Drug development Drugs Health Research Science Tuberculosis (TB)

July 25, 2018 Prasad Ravindranath

NCL-led team improves stability, bioavailability of FDC drug for TB

By turning to crystal engineering, the NCL-led team of researchers has improved the physical stability and bioavailability of a fixed-dose combination

Drug development Health Public Health Research Science Tuberculosis (TB)

July 7, 2018 Prasad Ravindranath

IGIB researchers find ways to reduce TB’s tissue-damaging effects

IGIB researchers have for the first time discovered that necrosis in granulomas result in the development of lipid-rich foamy macrophages,

Drug development Health Research Science

December 9, 2017 Prasad Ravindranath

IIT Guwahati researchers create bioartificial liver using silk

IIT Guwahati researchers have created a bioartificial liver model grown within a 3D silk scaffold. The scaffold made by mixing mulberry and

Drug development Medicine Research Science

October 7, 2017 Prasad Ravindranath

IIT Kanpur researchers make antibodies for treating a few genetic diseases

The antibodies will prevent the trafficking of the GPCR receptors from the membrane surface to inside of the cells thus

Dengue Drug development Drugs Health Medicine Public Health Zika

June 27, 2017 Prasad Ravindranath

Sun Pharma, NIV to jointly test drugs for Zika, chikungunya and dengue

Sun Pharmaceutical Industries Ltd and the National Institute of Virology (NIV), Pune signed an agreement for testing phytopharmaceutical, biologic and

Science Chronicle

Science Chronicle

PURE: An AI Tool Makes Designing Safer, More Effective Medicines Easier

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FDA uncovers ‘significant’ data falsification by Indian company, rejects all studies

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IIT Roorkee finds new drug target for antibiotic resistant bacteria Acinetobacter baumannii

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NCL-led team improves stability, bioavailability of FDC drug for TB

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IGIB researchers find ways to reduce TB’s tissue-damaging effects

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IIT Guwahati researchers create bioartificial liver using silk

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IIT Kanpur researchers make antibodies for treating a few genetic diseases

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Sun Pharma, NIV to jointly test drugs for Zika, chikungunya and dengue

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