April 1, 2026

Science Chronicle

A Science and Technology Blog

April 1, 2026

Science Chronicle

A Science and Technology Blog

Author: Lancelot Pinto

Drug safetyFixed dose combination drugsGeneric medicines

Why is irrational use of monteleukast as a combination drug continuing despite serious adverse effects?

Most antihistamines are sold as generics and are inexpensive. On the other hand, irrational combinations with montelukast sell at two-four times the cost of an antihistamine alone. The drug combinations are nothing but a sinister way to profiteer from common conditions. The proof: sales of montelukast as a standalone drug dropped 14%, while sales of combinations increased by 25% in 2023-24, with close to 200 registered brands selling combinations

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