One Protein, Two Cures: Harnessing Sclerostin’s Dual Nature to Tackle Osteoporosis, Osteoarthritis
Sclerostin plays a crucial role in bone formation but restrains abnormal bone growth in joints, which can worsen osteoarthritis. This paradox inspired the design of two short peptides with opposite functions — one restores bone in osteoporosis, while the other protects cartilage in osteoarthritis
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