Hypertrophic cardiomyopathy: Unlike global cohorts, South Indians carry different pathogenic genetic signatures
Compared with global cohorts (43.23%), South Indian patients had fewer variants (15.77%) in the 12 definitive genes linked to hypertrophic cardiomyopathy, which is a major cause of sudden cardiac deaths in young athletes. Instead, a single gene (MYH6) from the limited and disputed genes category had higher prevalence of pathogenic variants in South Indian patients
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