December 9, 2025 – Science Chronicle

December 9, 2025 Prasad Ravindranath

Achal Agrawal, Research-Integrity Sleuth From India, Among ‘Nature’s 10 People Who Helped Shape Science In 2025’

The recognition by Nature has come just three years after Dr. Achal Agrawal began raising awareness about and reporting on research-integrity violations by Indian researchers through the Indian Research Watch (IRW), a volunteer-run non-profit organisation he founded in November 2022

Artificial intelligence (AI)Chemistry Drug analogues Drug designing Drug development

December 9, 2025 Abhor Gupta Karthik Raman

PURE: An AI Tool Makes Designing Safer, More Effective Medicines Easier

An AI tool developed by IIT Madras has made discovery of highly safe, effective drug analogues easily possible. In the case of the FDA-approved cancer drug Sorafenib, starting from its original structure, PURE produced hundreds of thousands of possible analogues, and then narrowed them down using basic drug-likeness filters. A manageable group of candidates that were selected exhibited docking scores comparable to, and in some cases, superior to those of Sorafenib

Science Chronicle

Science Chronicle

Day: December 9, 2025

Achal Agrawal, Research-Integrity Sleuth From India, Among ‘Nature’s 10 People Who Helped Shape Science In 2025’

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PURE: An AI Tool Makes Designing Safer, More Effective Medicines Easier

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